The idea to implement the establishment of the School of Pharmacy at the University of Cape Coast (UCC) was conceived in 2012 and efforts were made to recruit lecturers with a pharmacy background into various existing departments at UCC. By 2014, four lecturers with pharmacy background were at post in the Department of Biomedical Sciences, (then under the School of Biological Sciences but now located within the School of Allied Health Sciences) and the Department of Pharmacology in the School of Medical Sciences. Later on, a Curriculum Development Committee (CDC) made up of Prof. Johnson Nyarko Boampong, Prof. Martins Ekor, Dr. Elvis Ofori Ameyaw, Dr. Ernest Obese, Dr. Robert Peter Biney, and Dr. Joseph Kizzie Hayford (then Deputy Director of University Health Services) was tasked to develop a PharmD curriculum for the College of Health and Allied Sciences (CoHAS), UCC. The first draft of the curriculum was ready by 2015 and a stakeholders’ consultative meeting with representatives from the Pharmacy Council of Ghana, Industrial Pharmacists Association, Pharmaceutical Society of Ghana (PSGh), and other lecturers of the University was organized by the CDC at Samrit Hotel in Cape Coast. The first set of documents consisting of the Proposal to establish UCC School of Pharmacy and Pharmaceutical Sciences (SoPPS) and the UCC PharmD curriculum were presented to UCC Academic Board in 2017. In May 2018, the Governing Council of the University of Cape Coast approved the proposal to establish SoPPS to train pharmacists. The UCC Council mandated an Implementation Committee headed by the then Provost of CoHAS, Prof. Johnson Nyarko Boampong to implement the establishment of SoPPS and ensure the running of the Pharm D programme. The other members of the committee included Prof. David Kofi Essuman (Dean, School of Physical Sciences), Prof. Edward Marfo Yiadom (Dean, School of Business), Dr. Joseph Tawiah Turkson (Director of Pharmaceutical Services, Cape Coast Teaching Hospital), and Dr. Yaw Adu Gyamfi, (CEO of Danadams Pharmaceuticals) and the first Faculty Officer for SoPPS, Mrs. Rebecca Asiedu Owusu as Secretary. Between 2018 and 2019, the School secured the relevant accreditations and approvals from The National Council for Tertiary Education (NCTE), National Accreditation Board (NAB), and Pharmacy Council to train Doctor of Pharmacy students at the University of Cape Coast. In preparation for its maiden students, Prof. David Darko Obiri was appointed as the first Dean of SoPPs. The School admitted fifty-three (53) individuals, who are the premier PharmD students for the 2019/2020 academic year comprising 25 males and 28 females.