The Southern Campus or Old Site is uniquely situated in the heart of the hilly settlements of “Apewosika” and “Kokoado” in the Cape Coast metropolis close to the shores of the Atlantic Ocean, providing a daily comfortable sea breeze. The site sits on high ground above sea level providing a beautiful bird’s eye view of the ocean. The setting up of the University campus within these communities has opened them up to a lot of socio-economic activities.

The University’s Central Administration Block, the Adehye Hall only female hall of residence, the Atlantic Hall and the Oguaa Hall are located here.

Various useful university facilities providing service to the population beyond the university community are also situated on this side of campus. One of such facility is the University Hospital, which provides quality health care to members of the university community and the general public.