This course introduces students to an in-depth study of the function and structural moiety of organic macromolecules of biological relevance. Topics to be discussed in this course will revolve around classification carbohydrates, stereoisomerism in carbohydrates, polyfunctional chemistry of simple sugars, cellulose and its derivatives, enzymatic glycogen hydrolysis, conversion of ATP to ADP, and proteins (classification, amino acids, peptides, determination of protein structure), nucleic acids, nucleosides, nucleotides, and synthetic polymers.
The course focuses on providing fundamental understanding of the structural features of biomolecules and the application of analytical chemistry techniques for the recognition and detection of biomolecular interactions. Topics to be discussed in the course will include the Central Dogma, Flow of Genetic information, Polymerase Chain Reaction (PCR) Technology, Enzymes as analytical reagents, quantitative immunoassays, biosensors, enzyme-linked immunosorbent assay, chromatography, spectroscopy and microscopy of biomolecules, and validation of new bioanalytical methods.
This course covers various aspects of spectroscopy particularly, electronic spectroscopy of atoms, ions and complex molecules, vibrational, rotational and laser spectroscopy, as well as, spectral interpretation and analysis of samples using molecular spectroscopic tools. Terms symbols for free atoms and ions, spectroscopic interpretation of colours of complexes, and elementary molecular orbital theory will be discussed. Broadly speaking, it provides a general overview of the concepts of absorption, emission, vibration, rotation, resonance and electron spin. Instrumental methods to be covered in this course will include UV-Vis spectroscopy, fluorescence, infrared spectroscopy, Raman spectroscopy, nuclear magnetic resonance, and mass spectrometry.
This course is intended to give students an insight into the principle governing how and why organic chemical reactions take place, as well as the survey of preparative methods in organic chemistry and their application to the synthesis of complex molecules. It will largely focus on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or agrochemical significance. Nucleophilic, electrophilic, elimination and addition reaction will also be covered.
This course seeks to introduction students to the chemistry of the excited state and the consequences of absorption of light by molecules and extensions into the photochemistry of biological system. View in the perspective of a physical organic chemistry course, it will allow students to reasonably evaluate the reactivity of an excited state and to analyze its monomolecular fate (photophysics), as well as, its bimolecular interactions. It will also provide an understanding of principles underlying photochemical reactions such as photosynthesis, and an appreciation of light – initiated chemical processes, fluorescence, phosphorescence, and quantum yields and applications of photochemistry to organic systems.
This course provides the students with fundamental understanding of the symmetry elements, their operations, group theory and formation of character table as well as applications in spectroscopy. Topics to be discussed will include identification and classification of symmetry elements and operations, point group, Schönflies and Herman-Mauguin symmetry classification systems, high and low symmetry groups, reducible and irreducible representation, character table, ans orthogonality theorem as well as application of point group symmetry to IR and Raman activity, identification of polarity and chirality and symmetry adapted linear combination of atomic orbitals.
This is a follow up course to CHE 201. Topics to be discussed will include: general properties of first and second row transition metals, and actinides and lanthanides series.
Application to catalysis especially for some industrial processes such as the Haber and Contact processes.
The course will expose students to preparation of standard reagents and inorganic complexes. Other experiments will focus on determination of heat of combustion, phase rule and concepts related to chemical kinetics. The use of other analytical methods such as gravimetric methods, complexometric titrations, electrochemical and spectroscopic methods will be performed.
The course will focus on basic concepts and problems in scientific investigation and research methodology, research techniques. Student will be introduced to sampling, data measurement, and proposal writing. The limitation of theory and methodology in analytical chemistry research will be highlighted. The use of instrumental analysis – GC, HPLC, IR, UV-Visible, NMR, MS and colorimetry will be studied.
This course provides students with insight into the chemistry of pharmaceuticals with in–depth explanation on the molecular mechanisms of drug action. It is also aimed at helping students to refine their skills in writing organic reaction mechanism and develop a better understanding of structure/ reactivity relationship found in organic molecules. The course will cover basic introductory materials which and govern drugs (discovery optimization and design) and their action, dermatologic and cosmetics applications.