This course is intended to give students an insight into the principle governing how and why organic chemical reactions take place, as well as the survey of preparative methods in organic chemistry and their application to the synthesis of complex molecules. It will largely focus on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or agrochemical significance. Nucleophilic, electrophilic, elimination and addition reaction will also be covered.
This course seeks to introduction students to the chemistry of the excited state and the consequences of absorption of light by molecules and extensions into the photochemistry of biological system. View in the perspective of a physical organic chemistry course, it will allow students to reasonably evaluate the reactivity of an excited state and to analyze its monomolecular fate (photophysics), as well as, its bimolecular interactions. It will also provide an understanding of principles underlying photochemical reactions such as photosynthesis, and an appreciation of light – initiated chemical processes, fluorescence, phosphorescence, and quantum yields and applications of photochemistry to organic systems.
This course provides the students with fundamental understanding of the symmetry elements, their operations, group theory and formation of character table as well as applications in spectroscopy. Topics to be discussed will include identification and classification of symmetry elements and operations, point group, Schönflies and Herman-Mauguin symmetry classification systems, high and low symmetry groups, reducible and irreducible representation, character table, ans orthogonality theorem as well as application of point group symmetry to IR and Raman activity, identification of polarity and chirality and symmetry adapted linear combination of atomic orbitals.
This is a follow up course to CHE 201. Topics to be discussed will include: general properties of first and second row transition metals, and actinides and lanthanides series.
Application to catalysis especially for some industrial processes such as the Haber and Contact processes.
The course will expose students to preparation of standard reagents and inorganic complexes. Other experiments will focus on determination of heat of combustion, phase rule and concepts related to chemical kinetics. The use of other analytical methods such as gravimetric methods, complexometric titrations, electrochemical and spectroscopic methods will be performed.
The course will focus on basic concepts and problems in scientific investigation and research methodology, research techniques. Student will be introduced to sampling, data measurement, and proposal writing. The limitation of theory and methodology in analytical chemistry research will be highlighted. The use of instrumental analysis – GC, HPLC, IR, UV-Visible, NMR, MS and colorimetry will be studied.
This course provides students with insight into the chemistry of pharmaceuticals with in–depth explanation on the molecular mechanisms of drug action. It is also aimed at helping students to refine their skills in writing organic reaction mechanism and develop a better understanding of structure/ reactivity relationship found in organic molecules. The course will cover basic introductory materials which and govern drugs (discovery optimization and design) and their action, dermatologic and cosmetics applications.
The course presents a broad survey of the phenomena isomerism, optical isomerism due to independent asymmetric carbon atoms, and stereoisomerism of compounds containing identical asymmetric carbons atoms. Topics to be discussed will include asymmetry of inorganic elements, alkenes, alkylidene, cycloalkanes, spirans and biphenyl; dissymmetry of restricted rotation and molecular overcrowding; enantiomers; symmetry element; racemic modification; epimerization; and resolution. Other relevant topics such as absolute and configuration; Rectus and Sinister system; stereochemistry of simple derivatives of cyclopropane, cyclobutane, cyclopentane, and decalins; and acyclic and cyclic system will also be discussed.
The course will discuss the failures of classical mechanics and will introduce the students to photoelectric effect, Compton effect, wave-particle duality of light, and Heisenberg’s Uncertainty Principle as well as the Bohr atom. The course will consider the postulates and general principles of quantum mechanics, three-dimensional systems, perturbation theory, and the particle in a box. Other topics will include the hydrogen atom, multi-electron atom, molecular spectroscopies and their selection rules. Prerequisite: students are expected to take Level 100 and 200 Mathematics courses in Further Calculus and Differential Equations.
This course has a link to CHE 104 (Introductory Practical Organic Chemistry) and will enable students to be able to undertake a simple project work in organic chemistry using basic laboratory techniques such as separation, purification and identification of compounds of binary and tertiary mixtures. The course will also offer students the techniques involved in spectroscopic methods for the identification and total synthesis of simple organic compounds.